Treatment and prevention of mixed infections of gastro-intestinal nematodes, respiratory nematodes and certain arthropod parasites in sheep. Trials have shown that moxidectin is effective against certain strains of Haemonchus contortus, Teladorsagia circumcincta and Trichostrongylus spp. resistant to benzimidazoles. The product has a persistent action and protects sheep for a certain duration against infection or re-infection with the following parasites for the period indicated: Teladorsagia circumcincta 97 Days, Haemonchus contortus 111 Days, Trichostrongylus colubriformis 44 Days, Psoroptes ovis 60 Days. Persistent efficacy periods have not been established for parasite species other than those included in the list above. Therefore, re-infection of animals on pasture contaminated by parasites other than these remains possible before the 44 day minimum persistency period demonstrated for specific species. Dosage is 0.5ml/10kg bodyweight to give 1 mg moxidectin/kg bodyweight. The 50ml vial stoppers must not be broached more than 10 times. Use automatic syringe equipment for the 200ml and 500ml vials. To ensure administration of a correct dose, bodyweight should be determined as accurately as possible; accuracy of the dosing device should be checked. If animals are to be treated collectively rather than individually, they should be grouped according to their bodyweight and dosed accordingly, in order to avoid under- or overdosing. The injection should be administered as a single subcutaneous injection at the base of the ear using an 18 gauge, 25 - 40mm hypodermic needle. Contra-indications, warnings, etc. For Animal Treatment Only. Do not use in dairy sheep, at any stage of life.
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Do not use in sheep less than 15 kg bodyweight. Do not use in cases of hypersensitivity to the active substance or to any excipients.
Adverse reactions: Swelling and inflammation may be found at the injection site in some animals following treatment. The swelling generally disappears within 7 days of treatment and generally resolves without any medical treatment required. In rare cases, adverse reactions such as transitory salivation, depression, drowsiness and ataxia might occur. No particular treatment is required; these symptoms usually disappear within 24 to 48 hours. Special warnings: Cydectin 2% LA for Sheep has been formulated specifically for subcutaneous injection in the base of the ear of sheep and must not be given by any other route of administration or to any other species. Withdrawal period:
Meat and offal: 104 days. Milk: Not permitted for use in dairy sheep, at any stage of life. The withdrawal period is based solely on a single injection at the base of the ear