For the active immunisation of pregnant cows and heifers to raise antibodies against E. coli adhesion F5 (K 99) antigen, rotavirus and coronavirus. When calves are fed colostrum from vaccinated cows during the first week of life, these antibodies have been demonstrated to reduce the severity of diarrhoea caused by bovine rotavirus, bovine coronavirus and enteropathogenic E. coli F5 (K99) and to reduce the shedding of virus by calves infected with bovine rotavirus or bovine coronavirus. 

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